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DGBNCT-Boron Agents

Author: Martin Kellert and Evamarie Hey-Hawkins

1. Basic Requirements of BNCT – BSH and BPA

2. Development of Small Boron-containing Molecules as BNCT Agents
         2.1. Amino Acid Derivatives
         2.2. Nucleic Acid Derivatives
         2.3. Boronated Porphyrins and Their Analogs
         2.4. Carbohydrates
         2.5. Peptides
         2.6. DNA- or Mitochondria-targeting Molecules

3. Boron Compounds Conjugated with Biomolecules
         3.1. Boron-conjugated Growth Factors
         3.2. Boron-Conjugated Antibodies
         3.3. Boron-conjugated Proteins

4. Boronated Polymers, Liposomes, and Other Nanoparticles as Boron-delivery Systems
         4.1. Boronated Polymers and Micelles
         4.2. Boronated Biopolymers
         4.3. Emulsions
         4.4. Liposomes
         4.5. Boronated Nanoparticles
         4.6. Boronated Nanotubes

5. Strategy for MRI-guided BNCT

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